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PACA-008B
PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat)
Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 Trifluoroacetate salt
Size:1mg
P1(RMB):1098
MW:4024.8
One letter sequence:FTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
Molecular Formula:C182H300N56O45S
Description:This peptide is the fragment 6-38 of PACAP, which is a much more potent and selective inhibitor of PACAP-27-stimulated pituitary adenylate cyclase than PACAP (6-27). Ki values for the inhibition of the enzyme were 7 nM and 150 nM respectively.
Literature Reference:P.Robberecht et al., Mol. Pharmacol., 42, 347 (1992) P.Robberecht et al., Eur. J. Biochem., 207, 239 (1992) F.Ohno et al., Regul. Peptides, 126, 115 (2005) P. Robberecht, P. Gourlet, P. De Neef, M-C. Woussen-Colle, M-C. Vandermeers-Piret, A. Vandermeers, and J. Christophe, Eur. J. Biochem., 207, 239 (1992). (Original) A. Vandermeers, S. Vandenborre, X. Hou, P. De Neef, P. Robberecht, M-C. Vandermeers-Piret, and J. Christophe, Eur. J. Biochem., 208, 815 (1992). (Pharmacol.)
Cas:143748-18-9