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PANC-001B
Chromostatin, bovine
Ser-Asp-Glu-Asp-Ser-Asp-Gly-Asp-Arg-Pro-Gln-Ala-Ser-Pro-Gly-Leu-Gly-Pro-Gly-Pro
Size:1.0mg
P1(RMB):582
MW:1954
One letter sequence:SDEDSDGDRPQASPGLGPGP
Molecular Formula:C78H120N24O35
Description:Chromostatin-20 corresponding to the first 20 N-terminal amino acids of bovine chromogranin A that produces a dose-dependent inhibition of catecholamine secretion from cultured chromaffin cells in the range of 10-9 to 10-6 M (ID50 approx. 5nM). It also modulates endocrine of catecholamine-associated response.
Literature Reference:E. Galindo et al., Proc. Nat. Acad. Sci. USA, 88, 1426 (1991)
Cas:[133633-11-1]