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CASP-022A
Boc-Asp(OBzl)-CMK
Boc-Asp(OBzl)-CMK
Size:1.0mg
P1(RMB):153
MW:355.8
One letter sequence:Boc-D(OBzl)-CMK
Molecular Formula:C17H22ClNO5
Description:Inhibitor that penetrates cells and binds covalently to the active site of caspase-1 (ICE). At a concentration of 2.5 µM, it blocks caspase-1-mediated processing of mature interleukin-1β in a monocytic cell line by 85% without influencing tumor necrosis factor processing.
Literature Reference:N.Boudreau et al., Science, 267, 891 (1995)
Cas:[172702-58-8]