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ADRM-008B
Pro-Adrenomedullin (45-92), human
Glu-Leu-Arg-Met-Ser-Ser-Ser-Tyr-Pro-Thr-Gly-Leu-Ala-Asp-Val-Lys-Ala-Gly-Pro-Ala-Gln-Thr-Leu-Ile-Arg-Pro-Gln-Asp-Met-Lys-Gly-Ala-Ser-Arg-Ser-Pro-Glu-Asp-Ser-Ser-Pro-Asp-Ala-Ala-Arg-Ile-Arg-Val
Size:1.0mg
P1(RMB):2421
MW:5114.8
One letter sequence:ELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRV
Molecular Formula:C215H359N67O73S2
Description:The adrenomedullin (ADM) precursor fragment is used in diagnosing several disease states, such as the dysfunction of the cardiovascular system and sepsis. The released amounts of these peptides is a reflection of the stoichiometric generation of ADM and proADM. ADM cannot be easily determined directly, because of the masking by binding proteins, instability in serum and stickiness to surfaces.
Literature Reference:J.Struck et al., Peptides , 25, 1369 (2004)
Cas:166798-69-2